62 destinations have scheduled flights from RDU, about 1,417 departures a week. Weekly frequencies come from airline schedules and observed departures, not live status.
| Destination | Flights per week | Airlines | Typical duration |
|---|---|---|---|
| New York (LGA) | 138 | Delta Air Lines, American Airlines, Frontier Airlines, Inc. | — |
| Orlando International (MCO) | 85 | Delta Air Lines, Frontier Airlines, Inc., Southwest Airlines Co., Mexicana | — |
| Chicago O'hare International (ORD) | 85 | American Airlines, Envoy Air Inc., United Airlines, Frontier Airlines, Inc. | — |
| Philadelphia International (PHL) | 81 | American Airlines, Frontier Airlines, Inc., UPS Airlines | — |
| Nashville International (BNA) | 70 | American Airlines, Southwest Airlines Co., Delta Air Lines | — |
| Charlotte Douglas (CLT) | 65 | American Airlines | — |
| Ronald Reagan Washington National Airport (DCA) | 65 | American Airlines, Envoy Air Inc., Delta Air Lines | — |
| Newark Liberty International (EWR) | 58 | United Airlines, Delta Air Lines, Spirit Airlines | — |
| John F Kennedy International (JFK) | 55 | American Airlines, Delta Air Lines, JetBlue, Republic Airline Inc.. | — |
| Hartsfield-jackson Atlanta International (ATL) | 50 | Delta Air Lines, Frontier Airlines, Inc. | — |
| Miami International Airport (MIA) | 47 | American Airlines, Envoy Air Inc., Frontier Airlines, Inc. | — |
| Dallas/Fort Worth International (DFW) | 46 | American Airlines, Frontier Airlines, Inc. | — |
| Baltimore/Washington International Thurgood Marshall (BWI) | 43 | Southwest Airlines Co. | — |
| Logan International (BOS) | 38 | JetBlue, Delta Air Lines | — |
| Denver International (DEN) | 31 | Southwest Airlines Co., Frontier Airlines, Inc., United Airlines | — |
| Tampa International (TPA) | 28 | Mexicana, Frontier Airlines, Inc., Delta Air Lines, Southwest Airlines Co. | — |
| Detroit Metropolitan Wayne County (DTW) | 25 | Delta Air Lines | — |
| Fort Lauderdale–Hollywood International (FLL) | 24 | JetBlue, Delta Air Lines, Spirit Airlines | — |
| Minneapolis - St. Paul International (MSP) | 22 | Delta Air Lines | — |
| Pittsburgh International (PIT) | 22 | American Airlines, Mexicana | — |
| Austin-bergstrom International (AUS) | 21 | Southwest Airlines Co., Delta Air Lines | — |
| George Bush Intercontinental (IAH) | 21 | United Airlines | — |
| Los Angeles International (LAX) | 20 | American Airlines, Delta Air Lines | — |
| Phoenix (PHX) | 19 | American Airlines, Southwest Airlines Co. | — |
| Midway (MDW) | 17 | Southwest Airlines Co. | — |
| Lambert-St. Louis International (STL) | 15 | Southwest Airlines Co. | — |
| William P Hobby (HOU) | 14 | Southwest Airlines Co. | — |
| Washington Dulles International (IAD) | 13 | United Airlines | — |
| Love Field (DAL) | 12 | Southwest Airlines Co. | — |
| San Francisco International (SFO) | 12 | United Airlines | — |
| Charles De Gaulle (CDG) | 11 | Air France | — |
| Luis Munoz Marin International (SJU) | 11 | Frontier Airlines, Inc., JetBlue | — |
| Indianapolis International (IND) | 9 | Delta Air Lines, Federal Express | — |
| Bradley International (BDL) | 7 | Mexicana | — |
| Akron/canton Regional (CAK) | 7 | Mexicana, Delta Air Lines | — |
| Cincinnati/Northern Kentucky (CVG) | 7 | Delta Air Lines | — |
| Heathrow (LHR) | 7 | American Airlines | — |
| Internacional Benito Juarez (MEX) | 7 | Aeromexico | — |
| Louis Armstrong New Orléans International Airport (MSY) | 7 | Mexicana | — |
| Fort Myers (RSW) | 7 | Mexicana | — |
| Louisville International (Standiford Field) (SDF) | 7 | UPS Airlines, Mexicana | — |
| Seattle-Tacoma International (SEA) | 7 | Alaska Airlines | — |
| Montreal (YUL) | 7 | Air Canada | — |
| Lester B. Pearson International (YYZ) | 7 | Air Canada | — |
| Frankfurt International Airport (FRA) | 6 | Lufthansa Cargo | — |
| New Haven (HVN) | 6 | Xtra Airways | — |
| Las Vegas (LAS) | 6 | Southwest Airlines Co. | — |
| Providence (PVD) | 6 | Mexicana | — |
| Keflavik International (KEF) | 5 | Icelandair | — |
| Tocumen International (PTY) | 5 | COPA Airlines | — |
| San Diego (SAN) | 5 | Alaska Airlines | — |
| Hopkins International (CLE) | 4 | Frontier Airlines, Inc. | — |
| Dublin International (DUB) | 4 | Aer Lingus | — |
| Memphis (MEM) | 4 | Federal Express | — |
| Rochester (ROC) | 4 | Mexicana, Xtra Airways | — |
| Albany International (ALB) | 2 | Mexicana | — |
| Cancún International (CUN) | 2 | Aeromexico | — |
| Long Island Mac Arthur (ISP) | 2 | Mexicana | — |
| Portsmouth (PSM) | 2 | Mexicana | — |
| Sarasota/Bradenton International (SRQ) | 2 | Mexicana | — |
| Piedmont Triad International (GSO) | 1 | Federal Express | — |
| Columbus (LCK) | 1 | Federal Express | — |
GET /routes returns each scheduled flight from RDU: airline, flight number, departure and arrival time, duration, days of operation and aircraft type.
https://www.goflightlabs.com/routes?access_key=YOUR_ACCESS_KEY&dep_iata=RDU
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